4-苯胺-1-苯甲基哌啶合成路线 （共 15 条）
反应条件
1: 1,2-dichloro-ethane / 20 °C 2: sodium hydroxide / water View Scheme
参考文献
Gupta, Pradeep Kumar; Yadav, Shiv Kumar; Bhutia, Yangchen Doma; Singh, Poonam; Rao, Pooja; Gujar, Niranjan Laxman; Ganesan, Kumaran; Bhattacharya, Rahul
Medicinal Chemistry Research, 2013 , vol. 22, # 8 p. 3888 - 3896
反应条件
in toluene 3 h; Heating;
参考文献
Brine; Boldt; Huang; Sawyer; Carroll
Journal of Heterocyclic Chemistry, 1989 , vol. 26, # 3 p. 677 - 686
反应条件
1: toluene / 3 h / Heating 2: 95 percent / H2, conc. HCl / 10 percent Pd/C / ethanol / 50 °C / 2068.6 Torr 3: 2) HCl / 1) CH2Cl2, 2) diethyl ether View Scheme
参考文献
Brine; Boldt; Huang; Sawyer; Carroll
Journal of Heterocyclic Chemistry, 1989 , vol. 26, # 3 p. 677 - 686
参考文献
EP1559428 A1, ;
Page/Page column 32 ;
EP 1559428 A1
反应条件
potassium carbonate in chloroform
T=20°C; 20 h;
参考文献
Diouf; Gadeau; Chelle; Gelbcke; Talaga; Christophe; Gillard; Massingham; Guyaux
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 18 p. 2535 - 2539
