N-苄氧羰基-L-谷氨酸合成路线 （共 80 条）
反应条件
pyridine Erwaermen des Reaktionsprodukts mit wss. NaOH;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 575, p. 217,230
反应条件
Bacillus licheniformis Glu-specific endopeptidase (BL-GSE); sodium chloride; calcium chloride T=25°C; Condensation; pH=8.0; Product distribution; Further Variations:Temperatures;
参考文献
Wehofsky, Nicole; Haensler, Marion; Kirbach, Sebastian W.; Wissmann, Johannes-Dieter; Bordusa, Frank
Tetrahedron Asymmetry, 2000 , vol. 11, # 11 p. 2421 - 2428
参考文献
Journal of Biological Chemistry, , vol. 115, p. 593,607
参考文献
Journal of Biological Chemistry, , vol. 111, p. 225,243
Journal of Biological Chemistry, , vol. 115, p. 593,596, 599
参考文献
Journal of Biological Chemistry, , vol. 115, p. 593,607
反应条件
N,N-dicyclohexylamine; dicyclohexyl-carbodiimide 1.) THF, 0 deg C; Multistep reaction;
参考文献
Dolence, E. Kurt; Lin, Chia-En; Miller, Marvin J.; Payne, Shelley M.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 956 - 968
反应条件
1: alcalase-CLEA / tetrahydrofuran / 16 h / 37 °C / Molecular sieve 2: papain / N,N-dimethyl-formamide / 25 °C / pH 8 / aq. buffer 3: palladium 10 on activated carbon; hydrogen / methanol; water / 20 °C / 7500.75 Torr View Scheme
参考文献
de Beer, Roseri J.A.C.; Zarzycka, Barbara; Mariman, Michiel; Amatdjais-Groenen, Helene I.V.; Mulders, Marc J.; Quaedflieg, Peter J.L.M.; van Delft, Floris L.; Nabuurs, Sander B.; Rutjes, Floris P.J.T.
ChemBioChem, 2012 , vol. 13, # 9 p. 1319 - 1326
反应条件
1: 86 percent / camphorsulfonic acid / benzene / Heating 2: 63 percent / CF3COOH; Et3SiH / CHCl3 / 120 h 3: 63 percent / H2 / 10 percent Pd-C / ethanol / 20 °C View Scheme
参考文献
Aurelio, Luigi; Brownlee, Robert T. C.; Hughes, Andrew B.; Sleebs, Brad E.
Australian Journal of Chemistry, 2000 , vol. 53, # 5 p. 425 - 433
反应条件
triethylamine; 4-(N,N-dimethlyamino)pyridine in dichloromethane T=0°C; 2 h; without cat., 2h; Yields of byproduct given;
参考文献
Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668
反应条件
triethylamine; 4-(N,N-dimethlyamino)pyridine in dichloromethane T=0°C; 1 h; without cat., 2h; Yields of byproduct given;
参考文献
Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668
