N-苄氧羰基-L-谷氨酸合成路线 （共 80 条）
反应条件
1: acetic acid anhydride 2: methanol View Scheme
参考文献
Le Quesne; Young
Journal of the Chemical Society, 1950 , p. 1954,1958
反应条件
alcalase-CLEA in tetrahydrofuran T=37°C; 16 h; Molecular sieve;
参考文献
de Beer, Roseri J.A.C.; Zarzycka, Barbara; Mariman, Michiel; Amatdjais-Groenen, Helene I.V.; Mulders, Marc J.; Quaedflieg, Peter J.L.M.; van Delft, Floris L.; Nabuurs, Sander B.; Rutjes, Floris P.J.T.
ChemBioChem, 2012 , vol. 13, # 9 p. 1319 - 1326
参考文献
Morley,J.S.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 2410 - 2421
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Nefkens,G.H.L.; Nivard,R.J.F.
Recueil des Travaux Chimiques des Pays-Bas, 1964 , vol. 83, p. 199 - 207
反应条件
p-toluenesulfonic acid monohydrate; paraformaldehyde in ethyl acetate; toluene
参考文献
Choongwae Pharma Corporation
Patent: US2004/53331 A1, 2004 ;
反应条件
molecular sieve; toluene-4-sulfonic acid in toluene Heating / reflux;
参考文献
CHOONGWAE PHARMA CORPORATION
Patent: WO2004/108731 A1, 2004 ;
Location in patent: Page 73 ;
反应条件
boron trichloride in dichloromethane T=25°C; 0.333333 h;
参考文献
Allevi, Pietro; Cribiu, Riccardo; Anastasia, Mario
Tetrahedron Letters, 2004 , vol. 45, # 30 p. 5841 - 5843
反应条件
sodium hydroxide; aniline; papain Hydrogenolyse der dabei unveraendert zurueckbleibenden N-Carbobenzoxy-D-glutaminsaeure an Palladium in Methanol;
参考文献
Levintow et al.
Archives of Biochemistry, 1951 , vol. 31, p. 77,78
Full Text Show Details
Birnbaum et al.
Journal of Biological Chemistry, 1952 , vol. 194, p. 455,458
反应条件
1.1: 100 percent / p-toluenesulfonic acid / toluene / 1.67 h / Heating 2.1: 100 percent / oxalyl chloride; DMF / CH2Cl2 / 0.5 h / 20 °C 3.1: 48 percent / D2; lutidine / 5percent Pd/BaSO4 / tetrahydrofuran / 2 h / 20 °C 4.1: 18 percent / (R)-Alpine borane / tetrahydrofuran / 10 h / 20 °C 5.1: 78 percent / hydrochloric acid / H2O / 2 h / 100 °C 6.1: NosE gene from Escherichia coli; β-NAD; ZnSO4 / glycine / H2O / 5 h / 42 °C / pH 10 6.2: NosF gene from Escherichia coli / H2O / 0.25 h / pH 10 View Scheme
参考文献
Luesch, Hendrik; Hoffmann, Dietmar; Hevel, Joan M.; Becker, Julia E.; Golakoti, Trimurtulu; Moore, Richard E.
Journal of Organic Chemistry, 2003 , vol. 68, # 1 p. 83 - 91
反应条件
1: DCC 2: NH3 / methanol View Scheme
参考文献
Jones,J.K.N. et al.
Canadian Journal of Chemistry, 1961 , vol. 39, p. 1005 - 1016
反应条件
acylase-substances from pig's kidney; buffered aqueous solution by T=37°C;
参考文献
Levintow et al.
Archives of Biochemistry, 1951 , vol. 31, p. 77,78
Full Text Show Details
Birnbaum et al.
Journal of Biological Chemistry, 1952 , vol. 194, p. 455,458
