N-苄氧羰基-L-谷氨酸合成路线 （共 80 条）
参考文献
Fruton; Irving; Bergmann
Journal of Biological Chemistry, 1940 , vol. 133, p. 703
反应条件
1: ClCOOiBu 2: TFA 3: H2 / Pd View Scheme
参考文献
Kubica; Rzeszotarska; Midura-Nowaczek; Roszkowska-Jakimiec
Pharmazie, 2000 , vol. 55, # 11 p. 841 - 844
反应条件
pyridine; bis-[(trifluoroacetoxy)iodo]benzene 24 h; Ambient temperature;
参考文献
Anteunis, M. J. O.; Auwera, C. Van der; Vanfleteren, L.; Borremans, F.
Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 2 p. 135 - 148
反应条件
1: 98 percent 2: 90 percent / sodium methoxide / methanol / 2 h / 0 °C 3: 60 percent / lead tetraacetate, cupric acetate monohydrate / benzene / 15 h / Heating View Scheme
参考文献
Hanessian, Stephen; Sahoo, Soumya P.
Tetrahedron Letters, 1984 , vol. 25, # 14 p. 1425 - 1428
反应条件
1: DCC / tetrahydrofuran / 0 °C 2: dicyclohexylamine (DCHA) / tetrahydrofuran / 0 °C 3: 70percent perchloric acid / Ambient temperature 4: 100 percent / 1 M KOH / methanol View Scheme
参考文献
Dolence, E. Kurt; Minnick, Albert A.; Miller, Marvin J.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 2 p. 461 - 464
反应条件
triethylamine; 4-(N,N-dimethlyamino)pyridine in dichloromethane T=0°C; 2 h; without cat., 2h; Yields of byproduct given;
参考文献
Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668
反应条件
triethylamine; 4-(N,N-dimethlyamino)pyridine in dichloromethane T=0°C; 1 h; without cat., 2h; Yields of byproduct given;
参考文献
Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668
反应条件
1: p-TSA 2: NaOMe / methanol View Scheme
参考文献
Hanessian, Stephen; Sahoo, Soumya P.
Tetrahedron Letters, 1984 , vol. 25, # 14 p. 1425 - 1428
参考文献
Nefkens,G.H.L.; Nivard,R.J.F.
Recueil des Travaux Chimiques des Pays-Bas, 1964 , vol. 83, p. 199 - 207
反应条件
1: (i) ClCO2iBu, Et3N, THF, (ii) NH3 2: H2, AcOH / Pd-C / ethanol View Scheme
参考文献
Ressler,C.
Journal of the American Chemical Society, 1960 , vol. 82, p. 1641 - 1644
