N6-Cbz-L-赖氨酸合成路线 （共 62 条）
反应条件
(i) aq. H2SO4, (ii) aq. HCl; Multistep reaction;
参考文献
Journal of the Chemical Society. Perkin transactions 1, , vol. 16, p. 2180 - 2183
参考文献
Justus Liebigs Annalen der Chemie, , vol. 636, p. 117 - 131
反应条件
ruthenium trichloride; sodium periodate in tetrachloromethane; acetonitrile pH=3; 3 h;
参考文献
Ranganathan; Muraleedharan; Bhattacharyya; Kundu
Journal of the Indian Chemical Society, 1998 , vol. 75, # 10-12 p. 583 - 589
参考文献
Swallow et al.
Biochemical Journal, 1958 , vol. 70, p. 359,361
Full Text Show Details
Barrass; Elmore
Journal of the Chemical Society, 1957 , p. 3134,3139
反应条件
1: acetic acid anhydride / und Hydrieren des Reaktionsprodukts an Palladium 2: pyridine 3: aqueous HCl View Scheme
参考文献
Wolf et al.
Journal of the American Chemical Society, 1952 , vol. 74, p. 2002
反应条件
1: 40.4 percent / KMnO4, 1 M aq. H2SO4, 50percent aq. AcOH / 0.25 h / 10 - 15 °C 2: 81.5 percent / 1 N aq. HCl / 3 h / Heating 3: 68 percent / 20percent aq. AcOH / 3 h / Heating View Scheme
参考文献
Szirtes, Tamas; Kisfaludy, Lajos; Palosi, Eva; Szporny, Laszlo
Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1654 - 1658
反应条件
1: 89 percent / aq. NaOH / 2-methyl-propan-2-ol / Ambient temperature 2: H2 / 5percent Pd/C / methanol; H2O / 24 h / 2585.7 Torr 3: dimethylformamide / 120 h / Ambient temperature View Scheme
参考文献
Acosta, C. Kirk; Bahr, Martin L.; Burdett, James E.; Cessac, James W.; Martinez, Rudy A.; et al.
Journal of Chemical Research, Miniprint, 1991 , # 5 p. 914 - 934
反应条件
sodium hydroxide in water 1.) 0 deg C, 30 min; 2.) up to RT, 30 min;
参考文献
Chen, Francis M. F.; Benoiton, N. Leo
Canadian Journal of Chemistry, 1987 , vol. 65, p. 1224 - 1227
反应条件
in tetrahydrofuran; acetonitrile
参考文献
E. R. Squibb and Sons, Inc.
Patent: US4849414 A1, 1989 ;
反应条件
methyl-phenyl-thioether in trifluoroacetic acid T=25°C; 3 h; Yield given;
参考文献
Kiso, Yoshiaki; Ukawa, Kazuko; Nakamura, Shizuo; Ito, Kaoru; Akita, Tadashi
Chemical & Pharmaceutical Bulletin, 1980 , vol. 28, # 2 p. 673 - 676
