N6-Cbz-L-赖氨酸合成路线 （共 62 条）
反应条件
ruthenium trichloride; sodium periodate in tetrachloromethane; acetonitrile pH=3; 3 h;
参考文献
Journal of the Indian Chemical Society, , vol. 75, # 10-12 p. 583 - 589
反应条件
1: aq. NaOH / 1 h 2: H2 / Pd / aq. ethanol; acetic acid View Scheme
参考文献
Archiv der Pharmazie, , vol. 318, # 2 p. 120 - 127
反应条件
sodium hydroxide
T=0 - 50°C;
参考文献
Ogier, Julien; Arnauld, Thomas; Carrot, Geraldine; Lhumeau, Antoine; Delbos, Jean-Marie; Boursier, Claire; Loreau, Olivier; Lefoulon, Francois; Doris, Eric
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 17 p. 3902 - 3907
反应条件
potassium permanganate; sulfuric acid in acetic acid
0.5 h;
参考文献
Wisniewski, Kazimierz; Kolodziejczyk, Aleksandra S.
Organic Preparations and Procedures International, 1997 , vol. 29, # 3 p. 338 - 341
反应条件
1: 40.4 percent / KMnO4, 1 M aq. H2SO4, 50percent aq. AcOH / 0.25 h / 10 - 15 °C
2: 81.5 percent / 1 N aq. HCl / 3 h / Heating
3: 68 percent / 20percent aq. AcOH / 3 h / Heating
4: 92 percent / dicyclohexylcarbodiimide / ethyl acetate / 3 h / 0 - 5 °C
5: 86 percent / NEt3 / dimethylformamide / 2 h / 0 - 5 °C
View Scheme
参考文献
Szirtes, Tamas; Kisfaludy, Lajos; Palosi, Eva; Szporny, Laszlo
Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1654 - 1658
反应条件
1: triethylamine / dimethylformamide / 30 h / Ambient temperature
2: H2 / 10percent Pd/C / methanol; H2O / 22 h / 760 Torr / Ambient temperature
3: trifluoroacetic acid / CH2Cl2 / Ambient temperature
View Scheme
参考文献
Thierry; Papet; Saez-Servent; Plissonneau-Haumont; Potier; Lenfant
Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2122 - 2127
反应条件
(i), (ii) H2, Pd-C; Multistep reaction;
参考文献
Inoue,T. et al.
Bulletin of the Chemical Society of Japan, 1976 , vol. 49, p. 719 - 723
反应条件
sodium hydroxide; chloroacetyl chloride
Behandeln des Reaktionsprodukts mit wss. NH3;
参考文献
Rao et al.
Journal of Biological Chemistry, 1952 , vol. 198, p. 507,508
Full Text Show Details
Uchio; Izumiya
Mem. Fac. Sci. Kyushu Univ., 1958 , vol. <C> 3, p. 5,6
反应条件
(i) aq. NaHCO3, dioxane, (ii) aq. HCl, AcOH; Multistep reaction;
参考文献
Hartter
Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1976 , vol. 357, # 12 p. 1683 - 1693
反应条件
2: palladium/charcoal; acetic acid; aqueous methanol / Hydrogenation
3: HCl
View Scheme
参考文献
Swallow et al.
Biochemical Journal, 1958 , vol. 70, p. 359,361
