1: t-butyl hydroperoxide / tetrahydrofuran; 2-methyl-propan-2-ol / 2 h 2: trimethylamine / toluene / 12 h / Ambient temperature 3: tetrabutylammonium fluoride / tetrahydrofuran / 48 h / Ambient temperature 4: sodium deoxycholate / 37 °C / phospholipaze in HEPES buffer (pH 8.0) View Scheme

1: t-butyl hydroperoxide / tetrahydrofuran; 2-methyl-propan-2-ol / 2 h 2: trimethylamine / toluene / 12 h / Ambient temperature 3: tetrabutylammonium fluoride / tetrahydrofuran / 48 h / Ambient temperature 4: sodium deoxycholate / 37 °C / phospholipaze in HEPES buffer (pH 8.0) View Scheme

Multi-step reaction with 2 steps 1: triethylamine / CHCl3 / 0.5 h / Ambient temperature2: tetrazole / acetonitrile; tetrahydrofuran / 3 h / Ambient temperature  

With  tert.-butylhydroperoxide in  tetrahydrofuran; tert-butyl alcohol 2 h;   

Multi-step reaction with 2 steps 1: t-butyl hydroperoxide / tetrahydrofuran; 2-methyl-propan-2-ol / 2 h2: trimethylamine / toluene / 12 h / Ambient temperature