1: 1.) 1,2-diiodoethane, samarium, Pd(PPh3)4, 2.) 0.2 M sodium methoxide / 1.) THF, RT, 8 h, 2.) methanol, 0 deg C, 4 h 2: 14.6 g / imidazole / dimethylformamide / 16 h / Ambient temperature 3: 84 percent / diethylamine, CuI, bis<triphenylphosphine>palladium(II) acetate / dimethylformamide / 1.5 h / Ambient temperature 4: 70 percent / tetrabutylammonium fluoride / tetrahydrofuran / 21 h / Ambient temperature 5: 90 percent / H2, quinoline / Lindlar catalyst / methanol; hexane / 0.33 h 6: acetone-d6 / 80.3 °C / var. temp.; kinetics, E(a), ΔG(excit.), ΔH(excit.), ΔS(excit.) View Scheme