1-乙基-4-(4-硝基苯基)哌嗪合成路线 （共 5 条）
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 20 p. 7066 - 7083
反应条件
N-ethyl-N,N-diisopropylamine in DMF (N,N-dimethyl-formamide) T=80°C; 16 h;
参考文献
US2004/122237 A1, ;
Page 180 ;
US 20040122237 A1
反应条件
palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene T=90°C; Hartwig-Buchwald reaction; Inert atmosphere;
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 7 p. 2917 - 2929
反应条件
potassium carbonate in dimethyl sulfoxide T=90°C; 12 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 75, p. 43 - 56
反应条件
hydrogen in methanol T=25°C; 7 h;
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 20 p. 7066 - 7083
