1-(2,4-二氟苯基)哌嗪合成路线 （共 2 条）
反应条件
tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; sodium t-butanolate in toluene T=110°C; 24 h; Inert atmosphere;
参考文献
Guo, Dong; Xia, Lizi; Van Veldhoven, Jacobus P. D.; Hazeu, Marc; Mocking, Tamara; Brussee, Johannes; Ijzerman, Adriaan P.; Heitman, Laura H.
ChemMedChem, 2014 , vol. 9, # 4 p. 752 - 761
反应条件
1: Buchwald-Hartwig cross coupling; 2: With hydrogenchloride in 1,4-dioxane
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 24 p. 7381 - 7384
