5-溴乙酰基-2-羟基苯甲醛合成路线 （共 8 条）
反应条件
aluminium trichloride in dichloromethane T=35°C; 15 h;
参考文献
Liu, Anqiu; Huang, Ling; Wang, Zhiren; Luo, Zonghua; Mao, Fei; Shan, Wenjun; Xie, Jiaxing; Lai, Kefang; Li, Xingshu
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1548 - 1552
反应条件
aluminium trichloride in dichloromethane 18 h; Heating;
参考文献
Rong, Yajing; Ruoho, Arnold E.
Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
反应条件
aluminium trichloride in dichloromethane 16 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Synthesis, , # 12 p. 966 - 972
反应条件
1: 71 percent / acetonitrile / 1 h / Heating; other solvent 2: NaBH4 / methanol / 36 h / Ambient temperature 3: 0.21 g / H2 / Pd/C / methanol / 10 h View Scheme
参考文献
Rong, Yajing; Ruoho, Arnold E.
Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
反应条件
1: sodium tetrahydroborate; acetic acid / 1 h / 10 °C 2: dichloromethane / 10 h / 20 °C View Scheme
参考文献
Liu, Anqiu; Huang, Ling; Wang, Zhiren; Luo, Zonghua; Mao, Fei; Shan, Wenjun; Xie, Jiaxing; Lai, Kefang; Li, Xingshu
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1548 - 1552
反应条件
1: 75 percent / propan-2-ol / 1.) -3 to 0 deg C, 30 min, 2.) room temp., 90 min 2: 2.) 12M aq. HCl / 1.) 2-propanol, 80 deg C, 1 h, 2.) 18 h 3: NaOCH3 / methanol / 0.08 h / 0 °C 4: H2 / 5percent Pd/c / methanol / 10 h / 3102.9 Torr View Scheme
参考文献
Babad; Carruthers; Jaret; Steinman
Synthesis, 1988 , # 12 p. 966 - 972
反应条件
1: 71 percent / acetonitrile / 1 h / Heating; other solvent
2: NaBH4 / methanol / 36 h / Ambient temperature
View Scheme
参考文献
Rong, Yajing; Ruoho, Arnold E.
Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
反应条件
sodium tetrahydroborate; acetic acid
T=8 - 20°C;
参考文献
Liu, Anqiu; Huang, Ling; Wang, Zhiren; Luo, Zonghua; Mao, Fei; Shan, Wenjun; Xie, Jiaxing; Lai, Kefang; Li, Xingshu
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1548 - 1552
