(S)-3-氨基-1-庚醇合成路线 （共 3 条）
反应条件
hydrogen; 5-palladium/activated carbon in ethanol T=20°C; P=3750.38 Torr; 144 h;
参考文献
JANSSEN RandD IRELAND; MC GOWAN, David; RABOISSON, Pierre Jean-Marie Bernard; EMBRECHTS, Werner; JONCKERS, Tim, Hugo, Maria; LAST, Stefaan, Julien; PIETERS, Serge, Maria, Aloysius; VLACH, Jaromir
Patent: WO2012/136834 A1, 2012 ;
Location in patent: Page/Page column 24 ;
反应条件
1.1: tetrahydrofuran / 16 h / 20 °C 2.1: n-butyllithium / tetrahydrofuran / 0.5 h / -78 °C 2.2: 2 h / -78 °C 3.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C 4.1: hydrogen / palladium 10 on activated carbon / methanol / 24 h / 50 °C / 2585.81 Torr View Scheme
参考文献
McGowan, David; Raboisson, Pierr Jeane-Marie Bernar; Embrechts, Werner; Jonckers, Tim Hugo Maria; Last, Stefaan Julien; Pieters, Serge Maria Aloysius; Vlach, Jaromir
Patent: US2014/45849 A1, 2014 ;
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C 2: hydrogen / palladium 10 on activated carbon / methanol / 24 h / 50 °C / 2585.81 Torr View Scheme
参考文献
McGowan, David; Raboisson, Pierr Jeane-Marie Bernar; Embrechts, Werner; Jonckers, Tim Hugo Maria; Last, Stefaan Julien; Pieters, Serge Maria Aloysius; Vlach, Jaromir
Patent: US2014/45849 A1, 2014 ;
