1-(吡嗪-2-基)环丙烷甲腈合成路线 （共 2 条）
反应条件
sodium hydride in N,N-dimethyl-formamide T=20°C; 18 h;
参考文献
PFIZER INC.; AHN, Kay; BOEHM, Markus; CABRAL, Shawn; CARPINO, Philip A.; FUTATSUGI, Kentaro; HEPWORTH, David; KUNG, Daniel W.; ORR, Suvi; WANG, Jian
Patent: WO2013/150416 A1, 2013 ;
Location in patent: Page/Page column 107 ;
反应条件
potassium hexamethylsilazane in tetrahydrofuran; toluene T=0 - 20°C; 4.08333 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2009/70485 A1, 2009 ;
Location in patent: Page/Page column 140 ;
WO 2009/070485 A1
