2,3-二氢-2,2,6-三甲基苯甲醛合成路线 （共 35 条）
反应条件
1: 30 percent / MCPBA / diethyl ether / 36 h / Ambient temperature 2: 100 percent / Br2 / CHCl3 / 0.25 h / -60 °C 3: 62 percent / Li2CO3 / dimethylformamide / 14 h / 105 °C View Scheme
参考文献
Tetrahedron, , vol. 54, # 12 p. 2753 - 2762
反应条件
1: 100 percent / Br2 / CHCl3 / 0.25 h / -60 °C 2: 62 percent / Li2CO3 / dimethylformamide / 14 h / 105 °C View Scheme
参考文献
Tetrahedron, , vol. 54, # 12 p. 2753 - 2762
反应条件
1: sodium bisulphate / H2O / 6 h / 0 - 15 °C 2: SOCl2, pyridine / benzene / 1 h / Heating 3: 1.8548 g / benzoyl peroxide, N-bromosuccinimide / CCl4 / 0.67 h / Heating 4: 27 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / benzene / 4 h / Heating 5: 63 percent / DIBAL-H / benzene / 2.5 h / Ambient temperature View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 70, # 7 p. 2094 - 2114
反应条件
1: 1.8548 g / benzoyl peroxide, N-bromosuccinimide / CCl4 / 0.67 h / Heating 2: 27 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / benzene / 4 h / Heating 3: 63 percent / DIBAL-H / benzene / 2.5 h / Ambient temperature View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 70, # 7 p. 2094 - 2114
反应条件
1: SOCl2, pyridine / benzene / 1 h / Heating 2: 1.8548 g / benzoyl peroxide, N-bromosuccinimide / CCl4 / 0.67 h / Heating 3: 27 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / benzene / 4 h / Heating 4: 63 percent / DIBAL-H / benzene / 2.5 h / Ambient temperature View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 70, # 7 p. 2094 - 2114
反应条件
1: 99 percent / NaBH4, CeCl3*7H2O / methanol / 0.08 h 2: 75 percent / p-toluenesulphonic acid / toluene / 30 h / Heating 3: 63 percent / DIBAL-H / benzene / 2.5 h / Ambient temperature View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 70, # 7 p. 2094 - 2114
反应条件
1: KOH; ethanol / 4 h 2: nBu4NCN / 8 h / 75 °C 3: 45 percent / ozone, sodium bicarbonate / ethyl acetate / 8 h / 0 °C 4: 92 percent / NaBH4 / ethanol / 1.5 h / Ambient temperature 5: conc. HCl / CH2Cl2 / 31 h 6: AIBN, tri-n-butyltin hydride / toluene / 2 h / Heating 7: 93 percent / ozone / ethyl acetate / 0.5 h / -78 °C 8: SOCl2 / methanol / 2 h 9: 99 percent / NaBH4, CeCl3*7H2O / methanol / 0.08 h 10: 75 percent / p-toluenesulphonic acid / toluene / 30 h / Heating 11: 63 percent / DIBAL-H / benzene / 2.5 h / Ambient temperature View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 70, # 7 p. 2094 - 2114
反应条件
1: nBu4NCN / 8 h / 75 °C 2: 45 percent / ozone, sodium bicarbonate / ethyl acetate / 8 h / 0 °C 3: 92 percent / NaBH4 / ethanol / 1.5 h / Ambient temperature 4: conc. HCl / CH2Cl2 / 31 h 5: AIBN, tri-n-butyltin hydride / toluene / 2 h / Heating 6: 93 percent / ozone / ethyl acetate / 0.5 h / -78 °C 7: SOCl2 / methanol / 2 h 8: 99 percent / NaBH4, CeCl3*7H2O / methanol / 0.08 h 9: 75 percent / p-toluenesulphonic acid / toluene / 30 h / Heating 10: 63 percent / DIBAL-H / benzene / 2.5 h / Ambient temperature View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 70, # 7 p. 2094 - 2114
反应条件
1: 46.2 percent / 30percent H2O2 / methanol / 0.17 h / 0 °C 2: 93 percent / CCl4 / 16 h / Heating 3: 88.5 percent / thionyl chloride, pyridine / CH2Cl2 / 0.08 h / 0 °C 4: 90.6 percent / 1N KOH / methanol / 4 h / Ambient temperature 5: 27.4 percent / chromium trioxide-pyridine complex / 1 h / Ambient temperature 6: 39.1 percent / pyridine / 2.5 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 29, # 1 p. 105 - 109
反应条件
1: 93 percent / CCl4 / 16 h / Heating 2: 88.5 percent / thionyl chloride, pyridine / CH2Cl2 / 0.08 h / 0 °C 3: 90.6 percent / 1N KOH / methanol / 4 h / Ambient temperature 4: 27.4 percent / chromium trioxide-pyridine complex / 1 h / Ambient temperature 5: 39.1 percent / pyridine / 2.5 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 29, # 1 p. 105 - 109
