N-苄氧羰基甘氨酰-L-脯氨酸合成路线 （共 19 条）
反应条件
post-proline endopeptidase in water; dimethyl sulfoxide T=37°C; 0.5 h; pH 7.5; Mechanism;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 47, # 4 p. 1139 - 1148
反应条件
tetrahydrofuran; methanol; sodium hydroxide
参考文献
Journal of the Chemical Society, , p. 3642,3646
参考文献
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 212, p. 72,79
反应条件
porcine prolyl oligopeptidase; tris(hydroxymethyl)methylamine hydrochloride in water; dimethyl sulfoxide pH=8; Enzymatic reaction; Kinetics;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 18, # 13 p. 4775 - 4782
反应条件
dicyclohexyl-carbodiimide anschliessend Behandeln mit L-Leucin-aethylester-hydrochlorid und Triaethylamin und Behandeln des Reaktionsprodukts mit Aceton und wss. NaOH;
参考文献
Kitaoka et al.
Bulletin of the Chemical Society of Japan, 1958 , vol. 31, p. 802,805
反应条件
1: Et3N / CH2Cl2 / 0.75 h / 0 °C 2: 1.03 g / Et3N / CH2Cl2 / 16 h / 20 °C 3: 85 percent / H2 / Pd-C / methanol; H2O / 18 h / 20 °C View Scheme
参考文献
Davis; Smith
Journal of Biological Chemistry, 1953 , vol. 200, p. 373,383
反应条件
methanol; palladium; acetic acid Hydrogenation;
参考文献
Nikolaev, S. V.; Burov, S. V.; Bakharev, V. D.; Makusheva, V. P.; Korkhov, V. V.
Chemistry of Natural Compounds, 1990 , vol. 26, # 6 p. 686 - 690
Khimiya Prirodnykh Soedinenii, 1990 , # 6 p. 805 - 810
反应条件
1: triethylamine; CHCl3; chlorocarbonic acid ethyl ester / anschliessend behandeln mit L-Prolin-benzylester 2: palladium; aqueous acetic acid; methanol / Hydrogenation View Scheme
参考文献
Poroschin et al.
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1959 , p. 1851; engl. Ausg. S. 1768, 1769
反应条件
dicyclohexyl-carbodiimide in ethylene glycol dimethyl ether
T=0°C; 12 h;
参考文献
Baldwin, Jack E.; Brown, David; Scudder, Paul H.; Wood, Mark E.
Tetrahedron Letters, 1995 , vol. 36, # 12 p. 2105 - 2108
