4-氯-3-甲氧基苯甲酸甲酯合成路线 （共 5 条）
反应条件
acetyl chloride T=0 - 20°C;
参考文献
El-Gamal, Mohammed I.; Choi, Hong Seok; Yoo, Kyung Ho; Baek, Daejin; Oh, Chang-Hyun
Chemical Biology and Drug Design, 2013 , vol. 82, # 3 p. 336 - 347
反应条件
in methanol; hexane; benzene T=0 - 20°C;
参考文献
Powers, James J.; Favor, David A.; Rankin, Trent; Sharma, Rashmi; Pandit, Chetan; Jeganathan, Azhwarsamy; Maiti, Samarendra N.
Tetrahedron Letters, 2009 , vol. 50, # 12 p. 1267 - 1269
反应条件
1: potassium carbonate / acetone / 1 h / Reflux 2: pyridine; potassium permanganate / water / 24 h / 50 °C 3: acetyl chloride / 0 - 20 °C View Scheme
参考文献
El-Gamal, Mohammed I.; Choi, Hong Seok; Yoo, Kyung Ho; Baek, Daejin; Oh, Chang-Hyun
Chemical Biology and Drug Design, 2013 , vol. 82, # 3 p. 336 - 347
反应条件
1: pyridine; potassium permanganate / water / 24 h / 50 °C 2: acetyl chloride / 0 - 20 °C View Scheme
参考文献
El-Gamal, Mohammed I.; Choi, Hong Seok; Yoo, Kyung Ho; Baek, Daejin; Oh, Chang-Hyun
Chemical Biology and Drug Design, 2013 , vol. 82, # 3 p. 336 - 347
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran; dichloromethane T=0 - 20°C; 2: With water; sodium sulfate in tetrahydrofuran; dichloromethane
参考文献
ChemoCentryx, Inc.
Patent: US2007/88036 A1, 2007 ;
Location in patent: Page/Page column 25 ;
US 20070088036 A1
