3-氧代-1-噁-4,9-二氮杂螺[5.5]十一烷-9-羧酸叔丁酯合成路线 (共 2 条)
反应条件
1: With potassium carbonate in water; ethyl acetate 2: With potassium tert-butylate in tert-butyl alcohol T=90°C;
参考文献
Stocks, Michael J.; Alcaraz, Lilian; Bailey, Andrew; Bowers, Keith; Donald, David; Edwards, Helen; Hunt, Fraser; Kindon, Nicholas; Pairaudeau, Garry; Theaker, Jill; Warner, Daniel J.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 24 p. 7458 - 7461
反应条件
1: With borane-THF in tetrahydrofuran T=55°C; 2: With N,N,N',N,-tetramethylethylenediamine in methanol 6 h; Reflux;
参考文献
Stocks, Michael J.; Alcaraz, Lilian; Bailey, Andrew; Bowers, Keith; Donald, David; Edwards, Helen; Hunt, Fraser; Kindon, Nicholas; Pairaudeau, Garry; Theaker, Jill; Warner, Daniel J.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 24 p. 7458 - 7461