N-苄氧羰基-L-苯丙氨酸合成路线 （共 122 条）
反应条件
1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane 2: hydrogen; palladium 10 on activated carbon / N,N-dimethyl-formamide 3: N-ethyl-N,N-diisopropylamine / dichloromethane 4: methanol / |Acidic conditions View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 21, # 4 p. 1018 - 1029
反应条件
1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane 2: hydrogen; palladium 10 on activated carbon / N,N-dimethyl-formamide 3: N-ethyl-N,N-diisopropylamine / dichloromethane 4: methanol / |Acidic conditions View Scheme
参考文献
Peuchmaur, Marine; Lacour, Marie-Agnes; Sevalle, Jean; Lisowski, Vincent; Touati-Jallabe, Youness; Rodier, Fabien; Martinez, Jean; Checler, Frederic; Hernandez, Jean-Francois
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 4 p. 1018 - 1029
反应条件
cell extract of Sphingomonas paucimobilis SC 16113 in water T=42°C; 20 h; Enzymatic reaction;
参考文献
Hemantha, Hosahalli P.; Sureshbabu, Vommina V.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 8 p. 2597 - 2601
反应条件
1,1'-carbonyldiimidazole in tetrahydrofuran
Inert atmosphere;
参考文献
Vishwanatha; Narendra; Chattopadhyay, Basab; Mukherjee, Monika; Sureshbabu, Vommina V.
Journal of Organic Chemistry, 2012 , vol. 77, # 6 p. 2689 - 2702
反应条件
pyridine
T=40°C; 1.5 h;
参考文献
Oyamada, Hidekazu; Saito, Takashi; Inaba, Shinsaku; Ueki, Masaaki
Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 4 p. 1422 - 1424
反应条件
sodium hydroxide; pepsin in methanol; water
T=40°C; pH=4;
参考文献
Tseng, Min-Jen; Wu, Shih-Hsiung; Wang, Kung-Tsung
Tetrahedron, 1983 , vol. 39, # 1 p. 61 - 66
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine in N,N-dimethyl-formamide
T=0 - 20°C;
参考文献
Kim, Dong Hee; Hong, Nam Joo
Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 1 p. 261 - 269
反应条件
1: BF3*OEt2
2: 80.8 percent / phosphate buffer; α-chymotrypsin / dimethylsulfoxide / 0.5 h / 30 °C / pH 8.0
View Scheme
参考文献
Salam, Sayed Mohiuddin Abdus; Kagawa, Ken-Ichi; Kawashiro, Katsuhiro
Tetrahedron Asymmetry, 2006 , vol. 17, # 1 p. 22 - 29
反应条件
tetrahydrofuran; 1-ethyl-piperidine
anschliessend Behandeln mit L-Phenylalanin-amid in Aethylacetat und wss. KHCO3;
参考文献
Blau; Waley
Biochemical Journal, 1954 , vol. 57, p. 538,539
反应条件
1: DCCI
2: aq. NaOH / 20 °C
View Scheme
参考文献
Kunieda, Takehisa; Higuchi, Tsunehiko; Abe, Yoshihiro; Hirobe, Masaaki
Tetrahedron, 1983 , vol. 39, # 20 p. 3253 - 3260
