6,7-二氢噻吩并[3,2-c]吡啶-2,5(4H)-二羧酸二乙酯合成路线 （共 3 条）
反应条件
1: 83 percent / 3.5 N aq. KOH / Heating 2: 95 percent / 47 percent aq. HBr / Heating View Scheme
参考文献
Kikuchi, Chika; Hiranuma, Toyokazu; Koyama, Masao
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 18 p. 2549 - 2552
反应条件
potassium hydroxide Heating;
参考文献
Kikuchi, Chika; Hiranuma, Toyokazu; Koyama, Masao
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 18 p. 2549 - 2552
反应条件
1: With potassium hydroxide 3 h; Reflux; 2: With hydrogenchloride in water T=0°C; Product distribution / selectivity;
参考文献
WO2009/124746 A1, ;
Page/Page column 121 ;
