(S)-N-苄基吡咯-3-甲醇对甲苯磺酸酯合成路线 （共 7 条）
反应条件
1: With 1,4-diaza-bicyclo[2.2.2]octane in tert-butyl methyl ether T=0 - 20°C; 16.3333 - 26.3333 h; 2: With sodium hydrogencarbonate in tert-butyl methyl ether; water; ethyl acetate T=20°C; 1 h;
参考文献
US2004/254219 A1, ;
Page 20 ;
反应条件
1,4-diaza-bicyclo[2.2.2]octane in tert-butyl methyl ether T=0 - 20°C; 16.3 - 21.3 h;
参考文献
WO2005/7645 A1, ;
Page 58 ;
WO 2005/007645 A1
反应条件
1: 1.4 g / ethyl acetate / 2 h / Heating 2: 14.6 g / aq. Na2CO3 / methanol / 4 h 3: pyridine / 48 h / 10 °C 4: ethanol / 20 h / 140 °C View Scheme
参考文献
Cesare, P. Di; Bouzard, D.; Essiz, M.; Jacquet, J. P.; Ledoussal, B.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4205 - 4213
反应条件
1: 1.4 g / ethyl acetate / 2 h / Heating 2: 14.6 g / aq. Na2CO3 / methanol / 4 h 3: pyridine / 48 h / 10 °C View Scheme
参考文献
Cesare, P. Di; Bouzard, D.; Essiz, M.; Jacquet, J. P.; Ledoussal, B.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4205 - 4213
反应条件
1: 1.4 g / ethyl acetate / 2 h / Heating 2: 14.6 g / aq. Na2CO3 / methanol / 4 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 22 p. 4205 - 4213
反应条件
in ethanol T=140°C; 20 h;
参考文献
Cesare, P. Di; Bouzard, D.; Essiz, M.; Jacquet, J. P.; Ledoussal, B.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4205 - 4213
反应条件
1: 1.4 g / ethyl acetate / 2 h / Heating 2: 14.6 g / aq. Na2CO3 / methanol / 4 h 3: pyridine / 48 h / 10 °C 4: ethanol / 20 h / 140 °C View Scheme
参考文献
Cesare, P. Di; Bouzard, D.; Essiz, M.; Jacquet, J. P.; Ledoussal, B.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4205 - 4213
