1: With boron tribromide in dichloromethane Inert atmosphere; 2: With sodium hydroxide in dichloromethane; water T=30 - 35°C; 0.5 h; Product distribution / selectivity;

Multi-step reaction with 2 steps 1.1: boron tribromide / dichloromethane / Inert atmosphere1.2: 0.5 h / 30 - 35 °C2.1: methanol / 2 h / Reflux; Resolution of racemate  

Stage #1: With  boron tribromide in  dichloromethane  Inert atmosphere; Stage #2: With  sodium hydroxide in  dichloromethane; water T=30 - 35°C;  Product distribution / selectivity;  Show Experimental Procedure