1-嘧啶-2-哌啶基-4-酮合成路线 (共 3 条)
反应条件
triethylamine in ethanol Heating / reflux; Product distribution / selectivity;
参考文献
LEXICON PHARMACEUTICALS, INC.
Patent: WO2008/58064 A1, 2008 ;
Location in patent: Page/Page column 17 ;
WO 2008/058064 A1
反应条件
sodium hydrogencarbonate in isopropyl alcohol 17 h; Heating / reflux; Product distribution / selectivity;
参考文献
WO2008/58064 A1, ;
Page/Page column 20 ;
WO 2008/058064 A1
反应条件
1: With sodium tetrahydroborate in methanol T=20°C; 0.166667 h; 2: With water in methanol; ethyl acetate
参考文献
Barbosa, Joseph; Dong, Li; Fink, Cynthia Anne; Wang, Jiancheng; Zipp, G. Gregory
Patent: US2006/258672 A1, 2006 ;
Location in patent: Page/Page column 18 ;