1: immobilized lipase Pseudomonas cepacia / ethyl acetate / 20 h / 20 °C / Inert atmosphere; Enzymatic reaction 2: potassium hydroxide / methanol; dichloromethane / 2 h / 0 °C 3: tetrahydrofuran; toluene / 1.5 h / -20 °C / Inert atmosphere 4: methanol; water / 0 - 20 °C 5: (+/-)-2-Ethyloxirane / ethanol / 6 h / Inert atmosphere; Reflux View Scheme

1: immobilized lipase Pseudomonas cepacia / ethyl acetate / 20 h / 20 °C / Inert atmosphere; Enzymatic reaction 2: tetrahydrofuran; toluene / 1.5 h / -20 °C / Inert atmosphere 3: methanol; water / 0 - 20 °C 4: (+/-)-2-Ethyloxirane / ethanol / 6 h / Inert atmosphere; Reflux View Scheme