1: methylhydrazine; formic acid ethyl ester in ethanol T=0°C; Vilsmeier type formylation; Reflux; 2: ethyl 3-oxo-hexanoate in ethanol Reflux; 3: With sodium ethanolate in ethanol Knoevenagel type condensation; Reflux; regioselective reaction;

1: 95 percent / 1 h / Heating 2: methanol / 1) 0 deg C, 15 min.; 2) room temp., 1 h View Scheme

in methanol 1) 0 deg C, 15 min.; 2) room temp., 1 h; Title compound not separated from byproducts;