1.1: potassium carbonate / N,N-dimethyl-formamide / -20 °C 2.1: trifluoroacetic anhydride / dichloromethane / 0.17 h / 0 °C 2.2: 20 °C 3.1: sodium methylate / methanol; dichloromethane / 0.5 h 4.1: potassium carbonate; tetrabutylammomium bromide / chloroform; water / 1 h / 50 °C 4.2: 24 h / 50 °C 5.1: 10 Pd/C; acetic acid; hydrogen / ethyl acetate / 4 h / 760.05 Torr 6.1: sodium methylate / methanol; dichloromethane / 0.5 h View Scheme