(3,4-二甲氧基苯基)(4-甲基苯基)甲酮合成路线 （共 6 条）
反应条件
tin(IV) chloride
T=60°C; Friedel Crafts acylation; 4 h;
参考文献
Belluti, Federica; Piazzi, Lorna; Bisi, Alessandra; Gobbi, Silvia; Bartolini, Manuela; Cavalli, Andrea; Valenti, Piero; Rampa, Angela
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 3 p. 1341 - 1348
反应条件
PPA
T=120°C; Friedel-Crafts acylation; 0.0125 h; microwave irradiation;
参考文献
Learmonth, David A.
Synthetic Communications, 2002 , vol. 32, # 18 p. 2757 - 2762
反应条件
aluminium trichloride
参考文献
Celgene Corporation
Patent: US5929117 A1, 1999 ;
反应条件
1: 38 percent / potassium 12-tungstocobalt(III)ate; sodium tartrate buffer / H2O / 6 h / pH 4.0
View Scheme
参考文献
Bietti, Massimo; Lanzalunga, Osvaldo
Journal of Organic Chemistry, 2002 , vol. 67, # 8 p. 2632 - 2638
反应条件
1: 38 percent / potassium 12-tungstocobalt(III)ate; sodium tartrate buffer / H2O / 6 h / pH 4.0
View Scheme
参考文献
Bietti, Massimo; Lanzalunga, Osvaldo
Journal of Organic Chemistry, 2002 , vol. 67, # 8 p. 2632 - 2638
反应条件
1: 68 percent / HNO3; AcOH / 0.5 h / 0 - 20 °C
2: 73 percent / Fe; AcOH / H2O; ethyl acetate / 6 h / Heating
View Scheme
参考文献
Butin, Alexander V.; Smirnov, Sergey K.; Stroganova, Tatyana A.; Bender, Wolfgang; Krapivin, Gennady D.
Tetrahedron, 2007 , vol. 63, # 2 p. 474 - 491
