4-氰基-3-苯丙酸乙酯合成路线 （共 14 条）
反应条件
palladium monocarbide in tetrahydrofuran
参考文献
Takeda Chemical Industries, Ltd.
Patent: US6235731 B1, 2001 ;
反应条件
1: With N,N-dicyclohexylmethylamine; tetrabutylammomium bromide in N,N-dimethyl-formamide T=120°C; Heck reaction; 4 h; 2: With hydrogenchloride in water; ethyl acetate T=20°C; chemospecific reaction;
参考文献
European Journal of Organic Chemistry, , # 18 p. 3102 - 3106
反应条件
manganese; water; trifluoroacetic acid; Co(2,2'-bipyridine)Br2; lithium bromide in pyridine; N,N-dimethyl-formamide T=80°C;
参考文献
Journal of Organic Chemistry, , vol. 71, # 16 p. 6130 - 6134
反应条件
1-methyl-pyrrolidin-2-one; bis(acetylacetonate)nickel(II); 1-(trifluoromethyl)-4-vinylbenzene in tetrahydrofuran T=-15°C; 5 h;
参考文献
Giovannini; Knochel
Journal of the American Chemical Society, 1998 , vol. 120, # 43 p. 11186 - 11187
反应条件
manganese; water; trifluoroacetic acid; Co(2,2'-bipyridine)Br2; lithium bromide in pyridine; N,N-dimethyl-formamide T=50°C;
参考文献
Amatore, Muriel; Gosmini, Corinne; Perichon, Jacques
Journal of Organic Chemistry, 2006 , vol. 71, # 16 p. 6130 - 6134
反应条件
manganese; water; trifluoroacetic acid; Co(2,2'-bipyridine)Br2; lithium bromide in pyridine; N,N-dimethyl-formamide T=50°C;
参考文献
Amatore, Muriel; Gosmini, Corinne; Perichon, Jacques
Journal of Organic Chemistry, 2006 , vol. 71, # 16 p. 6130 - 6134
反应条件
hydrogen; palladium on activated charcoal; ethylenediamine in tetrahydrofuran T=20°C; 24 h; atmospheric pressure;
参考文献
Maegawa, Tomohiro; Fujita, Yuki; Sakurai, Ai; Akashi, Akira; Sato, Mutsumi; Oono, Keiji; Sajiki, Hironao
Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 5 p. 837 - 839
反应条件
pyridine; [2,2']bipyridinyl; manganese; trifluoroacetic acid; cobalt(II) dibromide in N,N-dimethyl-formamide T=50°C; 2 h;
参考文献
Chemistry - A European Journal, , vol. 16, # 20 p. 5848 - 5852
反应条件
1: 3-(bromo)propionic acid ethyl ester With indium; copper(l) iodide; lithium chloride in tetrahydrofuran T=65°C; 12 h; 2: para-iodobenzonitrile With tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl acetamide T=90°C; 24 h;
参考文献
Shen, Zhi-Liang; Goh, Kelvin Kau Kiat; Wong, Colin Hong An; Yang, Yong-Sheng; Lai, Yin-Chang; Cheong, Hao-Lun; Loh, Teck-Peng
Chemical Communications, 2011 , vol. 47, # 16 p. 4778 - 4780
反应条件
pyridine; [2,2']bipyridinyl; triethylamine; cobalt(II) dibromide in acetonitrile T=70°C; electrochemical Heck reaction; Electrochemical reaction;
参考文献
Tetrahedron Letters, , vol. 43, # 34 p. 5901 - 5903
