4-氰基-3-苯丙酸乙酯合成路线 （共 14 条）
反应条件
pyridine; [2,2']bipyridinyl; manganese; trifluoroacetic acid; cobalt(II) dibromide in N,N-dimethyl-formamide T=65°C; 2 h;
参考文献
Amatore, Muriel; Gosmini, Corinne
Chemistry - A European Journal, 2010 , vol. 16, # 20 p. 5848 - 5852
反应条件
1: triethylamine / palladium diacetate; tris-(o-tolyl)phosphine / N,N-dimethyl-formamide / 1 h / 110 °C / Inert atmosphere 2: triethylamine; formic acid / palladium 10 on activated carbon / ethyl acetate; water / 1 h / 90 °C / Inert atmosphere; Reflux View Scheme
参考文献
Takeda Chemical Industries, Ltd.
Patent: US6235731 B1, 2001 ;
反应条件
1: With methanol; lithium borohydride in diethyl ether 3 h; Heating / reflux; 2: With ammonium chloride in diethyl ether; water
参考文献
ASTRAZENECA AB
Patent: WO2005/123747 A1, 2005 ;
Location in patent: Page/Page column 53 ;
WO 2005/123747 A1
