4-氨基四氢-2H-噻喃 1,1-二氧化物盐酸盐合成路线 （共 2 条）
反应条件
hydrogenchloride in ethyl acetate T=15 - 30°C; 19 h;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP2261213 A1, 2010 ;
Location in patent: Page/Page column 53 ;
EP 2261213 A1
反应条件
hydrogenchloride; palladium on carbon in methanol; water T=60°C; 48 h; Inert atmosphere;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED; DONG, Qing; LAWSON, John, David; WALLACE, Michael, B.; KANOUNI, Toufike
Patent: WO2010/144486 A1, 2010 ;
Location in patent: Page/Page column 92 ;
WO 2010/144486 A1
