1-ethyl-piperidine; cupric trifluoroacetate in methanol; water T=20°C; 14 h;

1: 1-iodo-1-(3,4,5-trimethoxyphenyl)ethylene With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); 1,8-diazabicyclo[5.4.0]undec-7-ene in water; N,N-dimethyl-formamide T=20°C; Sonogashira coupling; 0.0333333 h; 2: N-lt;2-(Trimethylsilylethynyl)phenylgt;methanesulfonamide in water; N,N-dimethyl-formamide T=20°C; 12 h;

copper(l) iodide; triethylamine in N,N-dimethyl-formamide T=80°C; 3 h;

tetrabutyl ammonium fluoride in tetrahydrofuran 3 h; Heating;