2-羟基-6-三氟甲基烟酰胺合成路线 （共 4 条）
反应条件
1: With ethanol; sodium 7 h; Heating / reflux; 2: With hydrogenchloride; water in ethanol
参考文献
Rosinger, Christopher; Ziemer, Frank; Auler, Thomas; Bickers, Udo; Hacker, Erwin
Patent: US2008/269052 A1, 2008 ;
Location in patent: Page/Page column 25 ;
反应条件
1: With sodium methylate in methanol 2 h; Heating / reflux; 2: With hydrogenchloride in water pH=1 - 3;
参考文献
WO2007/41052 A2, ;
Page/Page column 82 ;
WO 2007/041052 A2
反应条件
triethylamine; trichlorophosphate T=130°C; 4 h; Product distribution / selectivity;
参考文献
EP2251329 A1, ;
Page/Page column 5 ;
反应条件
hydrogenchloride; water T=103°C; 2 h;
参考文献
MERCK and CO., INC.
Patent: WO2007/41052 A2, 2007 ;
Location in patent: Page/Page column 82 ;
WO 2007/041052 A2
