1165952-91-9合成路线 （共 295 条）
反应条件
Yield given. Multistep reaction;
参考文献
Knolker; Bauermeister
Helvetica Chimica Acta, 1993 , vol. 76, # 7 p. 2500 - 2514
反应条件
NiCl2(PnBu3)2; diisobutyl-aluminum chloride in decalin
P=4085.5 Torr;
参考文献
Zhang, Aibin; RajanBabu
Journal of the American Chemical Society, 2006 , vol. 128, # 1 p. 54 - 55
反应条件
in diethyl ether
Irradiation;
参考文献
Meinwald,J.; Mazzocchi,P.H.
Journal of the American Chemical Society, 1966 , vol. 88, p. 2850 - 2851
反应条件
toluene-4-sulfonic acid in toluene
T=78°C; Inert atmosphere;
参考文献
Liu, Xin; Ou, Yingyong; Chen, Shaopeng; Lu, Xin; Cheng, Hao; Jia, Xian; Wang, Decai; Zhou, Guo-Chun
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 6 p. 2147 - 2153
反应条件
zeolite H-BEA in toluene
T=111°C; Title compound not separated from byproducts;
参考文献
Jimenez, Oriol; Mueller, Thomas E.; Schwieger, Wilhelm; Lercher, Johannes A.
Journal of Catalysis, 2006 , vol. 239, # 1 p. 42 - 50
反应条件
bis(acetylacetonate)nickel(II); diethylzinc in tetrahydrofuran; toluene
T=20°C; 2 h;
参考文献
Loh, Teck-Peng; Song, Hong-Yan; Zhou, Yan
Organic Letters, 2002 , vol. 4, # 16 p. 2715 - 2717
反应条件
1: With di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; tetra-(n-butyl)ammonium iodide; bis-diphenylphosphine in 1,2-dichloro-ethane
T=65°C; 15 h; Inert atmosphere;
2: With Dess-Martin periodane in dichloromethane
T=20°C; 0.5 h; Inert atmosphere;
参考文献
Bower, John F.; Patman, Ryan L.; Krische, Michael J.
Organic Letters, 2008 , vol. 10, # 5 p. 1033 - 1035
反应条件
bismuth trifluoromethanesulphonate; [Cu(I)(CH3CN)4]PF6; 1,2-bis-(diphenylphosphino)ethane in 1,4-dioxane
T=50°C; 18 h;
参考文献
Qin, Hongbo; Yamagiwa, Noriyuki; Matsunaga, Shigeki; Shibasaki, Masakatsu
Journal of the American Chemical Society, 2006 , vol. 128, # 5 p. 1611 - 1614
反应条件
1: 68 percent / t-BuOK / pentane / 4 h / 0 °C
2: 79 percent / m-chloroperbenzoic acid, NaHCO3 / CH2Cl2 / 1.) 0 deg C, 3 h, 2.) room temperature, overnight
3: n-Bu3SnH / benzene / Ambient temperature
4: 17 percent / tetrahydrofuran; hexane / 0.08 h / -70 °C / reaction at 0 deg C; electrocyclic ring opening of β-lithiocyclopropyloxirane, generationand trapping of (2Z,4E)-cyclohepta-2,4-dienol
View Scheme
参考文献
Coates, Robert M.; Last, Larry A.
Journal of the American Chemical Society, 1983 , vol. 105, # 25 p. 7322 - 7326
反应条件
1: 68 percent / t-BuOK / pentane / 4 h / 0 °C
2: 79 percent / m-chloroperbenzoic acid, NaHCO3 / CH2Cl2 / 1.) 0 deg C, 3 h, 2.) room temperature, overnight
3: n-Bu3SnH / benzene / Ambient temperature
4: 17 percent / tetrahydrofuran; hexane / 0.08 h / -70 °C / reaction at 0 deg C; electrocyclic ring opening of β-lithiocyclopropyloxirane, generationand trapping of (2Z,4E)-cyclohepta-2,4-dienol
5: 80 percent / pyridinium chlorochromate / CH2Cl2 / Ambient temperature
View Scheme
参考文献
Coates, Robert M.; Last, Larry A.
Journal of the American Chemical Society, 1983 , vol. 105, # 25 p. 7322 - 7326
