甲基3-氨基-1-氰基-1-苯基-1H-茚-2-羧酸酯合成路线 (共 3 条)
反应条件
potassium tert-butylate in N,N-dimethyl-formamide 3 h;
参考文献
Sommer, Michael Bech; Begtrup, Mikael; Boegesoe, Klaus Peter
Journal of Organic Chemistry, 1990 , vol. 55, # 16 p. 4822 - 4827
反应条件
multistep reaction: one pot alkylation and cyclization; reaction with other o-halogen substituted cyanoaromatics or other halogen esters;
参考文献
Sommer, Michael Bech; Begtrup, Mikael; Boegesoe, Klaus Peter
Journal of Organic Chemistry, 1990 , vol. 55, # 16 p. 4822 - 4827
反应条件
1: 1.) acetic acid, 2.) 60 percent aq. H2SO4 / 1.) 100 deg C, 2.) 110 deg C, 6 h 2: N-methylpyrrolidone / 1 h / 100 °C View Scheme
参考文献
Sommer, Michael Bech; Begtrup, Mikael; Boegesoe, Klaus Peter
Journal of Organic Chemistry, 1990 , vol. 55, # 16 p. 4822 - 4827