(R)-3-氨基-1,2,3,4-四氢咔唑合成路线 (共 11 条)
反应条件
1: 84 percent / triethylamine / CH2Cl2 / 1 h / Ambient temperature 2: 1.) 80percent sodium hydride (in mineral oil), 2.) 10percent potassium hydroxide / 1.) dimethylformamide, 2 h, room temperature, 2.) isopropanol, reflux, 16 h View Scheme
参考文献
Busto, Eduardo; Gotor-Fernandez, Vicente; Gotor, Vicente
Journal of Organic Chemistry, 2012 , vol. 77, # 10 p. 4842 - 4848