N-[(9H-芴-9-基甲氧基)羰基]-L-丙氨酰甘氨酸合成路线 （共 8 条）
反应条件
phosphate buffer in tert-butyl alcohol
T=35°C; alcalase;
参考文献
Chen; Hsiao; Chang; Wang
Synthetic Communications, 1992 , vol. 22, # 3 p. 391 - 398
反应条件
1: N-(9-fluorenylmethoxycarbonyl)glycine With piperidine in N,N-dimethyl-formamide
2: N-(9H-fluoren-9-ylmethyloxycarbonylamino)-L-alanine With benzotriazol-1-ol; diisopropyl-carbodiimide in N-methyl-formamide; N,N-dimethyl-formamide
参考文献
Biotempt B.V.
Patent: US2007/21347 A1, 2007 ;
Location in patent: Page/Page column 8 ;
反应条件
N-benzyl-N,N,N-trimethyl-ammonium chloride in chloroform
3 h; Ambient temperature;
参考文献
Chen; Wang
Journal of the Chemical Society - Series Chemical Communications, 1990 , # 15 p. 1045 - 1047
反应条件
1: dicyclohexylcarbodiimide / ethyl acetate; dimethylformamide / 6 h / Ambient temperature
2: diisopropylethylamine / CH2Cl2; dimethylformamide; ethyl acetate / 4 h / Ambient temperature
3: 91 percent / phosphate buffer / 2-methyl-propan-2-ol / 35 °C / alcalase
View Scheme
参考文献
Chen; Hsiao; Chang; Wang
Synthetic Communications, 1992 , vol. 22, # 3 p. 391 - 398
反应条件
montmorillonite K10 in dichloromethane
T=20°C; 3.5 h; Product distribution / selectivity;
参考文献
NATIONAL UNIVERSITY CORPORATION, TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY; JITSUBO CO., LTD.
Patent: WO2007/34812 A1, 2007 ;
Location in patent: Page/Page column 37-39; 42-43 ;
反应条件
1: diisopropylethylamine / CH2Cl2; dimethylformamide; ethyl acetate / 4 h / Ambient temperature
2: 91 percent / phosphate buffer / 2-methyl-propan-2-ol / 35 °C / alcalase
View Scheme
参考文献
Chen; Hsiao; Chang; Wang
Synthetic Communications, 1992 , vol. 22, # 3 p. 391 - 398
反应条件
1: zinc / tetrahydrofuran / 20 °C
2: water; calcium chloride; sodium hydroxide / isopropyl alcohol
View Scheme
参考文献
Ramesh; Raju; Srinivas; Sureshbabu; Vishwanatha; Hemantha
Rapid Communications in Mass Spectrometry, 2011 , vol. 25, # 14 p. 1949 - 1958
反应条件
trifluoroacetic acid
参考文献
Lozano, Jose Manuel; Lesmes, Liliana P.; Carreno, Luisa F.; Gallego, Gina M.; Patarroyo, Manuel Elkin
Molecules, 2010 , vol. 15, # 12 p. 8856 - 8889
