7-甲氧基-2,3-二氢-苯并[1,4]二噁英-6-甲醛合成路线 （共 7 条）
反应条件
trichlorophosphate T=100°C;
参考文献
Guillaumet, G.; Hretani, M.; Coudert, G.
Tetrahedron Letters, 1988 , vol. 29, # 22 p. 2665 - 2666
反应条件
copper dichloride in N,N-dimethyl-formamide T=100°C;
参考文献
Guillaumet, G.; Hretani, M.; Coudert, G.
Tetrahedron Letters, 1988 , vol. 29, # 22 p. 2665 - 2666
反应条件
1: 90 percent / NaOH / tetrabutylammonium bromide / H2O 2: 61 percent / Br2 / acetic acid / 0 °C 3: 49 percent / CuCl2 / dimethylformamide / 100 °C View Scheme
参考文献
Guillaumet, G.; Hretani, M.; Coudert, G.
Tetrahedron Letters, 1988 , vol. 29, # 22 p. 2665 - 2666
反应条件
1: 1) NaH / 1) DMF, r.t., 2) r.t. 2: 1) phosphorus oxychloride / 1) 0 deg C, 2) 60 deg C View Scheme
参考文献
Guillaumet, Gerald; Hretani, Mohamed; Coudert, Gerard; Averbeck, Dietrich; Averbeck, Simone
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 1 p. 45 - 51
反应条件
1: 61 percent / Br2 / acetic acid / 0 °C 2: 49 percent / CuCl2 / dimethylformamide / 100 °C View Scheme
参考文献
Taniguchi, Eiji; Yamauchi, Satoshi; Nagata, Shyuichirou; Ohnishi, Takeshi
Bioscience, Biotechnology, and Biochemistry, 1992 , vol. 56, # 2.3.4. p. 630 - 635
反应条件
1: 1.) NaNO2, H2SO4; 2.) H2O / 1.) 0 grad C; 2.) 80 grad C 2: 90 percent / KOH / Heating 3: 77 percent / POCl3 / 100 °C View Scheme
参考文献
Guillaumet, Gerald; Hretani, Mohamed; Coudert, Gerard; Averbeck, Dietrich; Averbeck, Simone
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 1 p. 45 - 51
反应条件
aluminium trichloride in dichloromethane 1 h; Ambient temperature;
参考文献
Guillaumet, G.; Hretani, M.; Coudert, G.
Tetrahedron Letters, 1988 , vol. 29, # 22 p. 2665 - 2666
