4-[(8-喹啉磺酰基)氨基]苯甲酸合成路线 （共 4 条）
反应条件
lithium hydroxide hydrate in tetrahydrofuran; water T=80°C;
参考文献
Salituro, Francesco G.; Saunders, Jeffrey; Yan, Shunqi
Patent: US2012/172349 A1, 2012 ;
Location in patent: Page/Page column 16-17 ;
反应条件
pyridine in dichloromethane T=20°C; 16 h; Inert atmosphere;
参考文献
AGIOS PHARMACEUTICALS, INC.; POPOVICI-MULLER, Janeta; SAUNDERS, Jeffrey, O.; ZAHLER, Robert; CIANCHETTA, Giovanni
Patent: WO2014/74848 A1, 2014 ;
Location in patent: Page/Page column 52; 53 ;
反应条件
1: pyridine / dichloromethane / 18 h / 20 °C / Inert atmosphere 2: water; lithium hydroxide hydrate / tetrahydrofuran / 12 h / 20 °C View Scheme
参考文献
Salituro, Francesco G.; Saunders, Jeffrey; Yan, Shunqi
Patent: US2012/172349 A1, 2012 ;
反应条件
1: pyridine / dichloromethane / 18 h / 20 °C / Inert atmosphere 2: water; lithium hydroxide hydrate / tetrahydrofuran / 12 h / 20 °C View Scheme
参考文献
Salituro, Francesco G.; Saunders, Jeffrey; Yan, Shunqi
Patent: US2012/172349 A1, 2012 ;
