perchloric acid in acetone 2 h; bath temperature 70 deg C;

perchloric acid in acetone 2 h; bath temperature 70 deg C;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3592982', constants.ctx, '0')">sodium methylate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '506008', constants.ctx, '0')">dimethyl sulfoxide</a> <br />T=50&deg;C;&nbsp;12&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 74 percent / PPTS / benzene / 96 h / Heating<br />2: N-bromosuccinimide / CCl₄ / Heating<br />3: 37 percent / N-methylmorpholine N-oxide, OsO₄ / tetrahydrofuran; acetonitrile; 2-methyl-propan-2-ol / 48 h / Ambient temperature<br />4: 96 percent / p-toluenesulfonic acid / CH₂Cl₂ / 4 h / Ambient temperature<br />5: 89 percent / sodium methoxide / dimethylsulfoxide / 12 h / 50 &deg;C<br /> <br /> &nbsp;