3beta-羟基孕甾-16-烯-20-酮-3-醋酸酯合成路线 （共 14 条）
反应条件
1: methanol; aqueous NaOH-solution; aqueous hydrogen peroxide / Erwaermen des Reaktionsprodukts mit Acetanhydrid und Pyridin 2: aqueous acetic acid; HBr 3: palladium/BaCO3; ethanol / Hydrogenation 4: NaBH4; ethanol / Beim Behandeln des Reaktionsprodukts mit Blei(IV)-acetat in Benzol 5: Hydrolysis View Scheme
参考文献
Toldy
Acta Chimica Academiae Scientiarum Hungaricae, 1958 , vol. 16, p. 411,414
反应条件
1.1: 98.07 percent / NH2OH*HCl; pyridine / 2 h / 65 - 68 °C 2.1: POCl3; pyridine / acetone / 0.5 h / 18 - 20 °C 2.2: 65 percent / aq. HCl / acetone / 30 h / -5 °C 3.1: 97 percent / NaBH4 / methanol / 1 h / 0 - 20 °C 4.1: 95 percent / NaOH / methanol / 0.17 h / Heating View Scheme
参考文献
Merlani; Amiranashvili; Men'Shova; Kemertelidze
Chemistry of Natural Compounds, 2007 , vol. 43, # 1 p. 97 - 99
反应条件
methanol; sodium hydroxide; dihydrogen peroxide Erwaermen des Reaktionsprodukts mit wss.-methanol. Kaliumcarbonat-Loesung oder wss.-methanol. Kaliumhydrogencarbonat-Loesung;
参考文献
Toldy
Acta Chimica Academiae Scientiarum Hungaricae, 1958 , vol. 16, p. 411,414
Full Text Show Details
Camerino et al.
Gazzetta Chimica Italiana, 1953 , vol. 83, p. 795,799
Full Text Show Details
Neher et al.
Helvetica Chimica Acta, 1958 , vol. 41, p. 1667,1691
Helvetica Chimica Acta, 1959 , vol. 42, p. 132,149
反应条件
1.1: 98.07 percent / NH2OH*HCl; pyridine / 2 h / 65 - 68 °C 2.1: POCl3; pyridine / acetone / 0.5 h / 18 - 20 °C 2.2: 65 percent / aq. HCl / acetone / 30 h / -5 °C View Scheme
参考文献
Toldy
Acta Chimica Academiae Scientiarum Hungaricae, 1958 , vol. 16, p. 411,414
