4-(3-硝基苯基)-3-氧代丁酸乙酯合成路线 （共 4 条）
反应条件
1,1'-carbonyldiimidazole in tetrahydrofuran
参考文献
Kori, Masakuni; Miki, Takashi; Nishimoto, Tomoyuki; Tozawa, Ryuichi
Patent: US2003/78251 A1, 2003 ;
反应条件
boron trifluoride diethyl etherate in diethyl ether
T=20°C; 0.5 h;
参考文献
Rao, D. Chandra; Reddy, D. Kumar; Shekhar; Chinababu; Rao, Ch. Bhujanga; Venkateswarlu
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2014 , vol. 53, # 3 p. 356 - 358
反应条件
triethylamine; magnesium chloride
1.) CH3CN, RT, 2 h, 2.) CH3CN, a) RT, overnight, b) reflux, 2 h; Yield givenMultistep reaction;
参考文献
Mai, Antonello; Artico, Marino; Sbardella, Gianluca; Massa, Silvio; Novellino, Ettore; Greco, Giovanni; Loi, Anna Giulia; Tramontane, Enzo; Marongiu, Maria Elena; La Colla, Paolo
Journal of Medicinal Chemistry, 1999 , vol. 42, # 4 p. 619 - 627
反应条件
pyridine
1.) CH2Cl2, RT, 1 h, 2.) reflux, 1 h; Yield given. Multistep reaction;
参考文献
Ohkubo; Kuno; Sakai; Sugiyama; Takasugi
Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 6 p. 1279 - 1285
