1H-咪唑-2-基(4-甲基苯)甲酮合成路线 （共 3 条）
反应条件
hydrogenchloride in tetrahydrofuran
参考文献
Sumitomo Pharmaceuticals Company, Limited
Patent: EP1479384 A1, 2004 ;
反应条件
1: With triethylamine in pyridine T=40°C; 2: With sodium hydroxide in water
参考文献
Ushiroda, Kantaro; Maruta, Katsunori; Takazawa, Takeshi; Nagano, Tomokazu; Taiji, Mutsuo; Kohno, Tetsuya; Sato, Yasuhiro; Horai, Shinji; Yanagi, Kazunori; Nagata, Ryu
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 7 p. 1978 - 1982
反应条件
n-butyllithium 1.) Et2O, hexane, -70 deg C, 1 h, 2.) 25 deg C, a few hours; Yield given. Multistep reaction;
参考文献
Katritzky, Alan R.; Rewcastle, Gordon W.; Fan, Wei-Qiang
Journal of Organic Chemistry, 1988 , vol. 53, # 24 p. 5685 - 5689
