2-(4-氨基苯氧基)-2-甲基丙酸合成路线 （共 12 条）
反应条件
potassium hydroxide 0.5 h; Heating;
参考文献
Center for Innovative Technology
Patent: US5591892 A1, 1997 ;
反应条件
sodium hydroxide; bromine in water T=75°C; 0.5 h;
参考文献
Lalezari, Iraj; Lalezari, Parviz
Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2352 - 2357
反应条件
1: 48 percent / NaOH / 4 h / Heating 2: 87 percent / 10percent KOH / 0.5 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 10 p. 2352 - 2357
参考文献
Acta Chemica Scandinavica (1947-1973), , vol. 7, p. 596,599
反应条件
potassium hydroxide 0.5 h; Heating;
参考文献
Lalezari, Iraj; Lalezari, Parviz
Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2352 - 2357
反应条件
1: NaOH 2: H2, aq. HCl / Pd-C / ethanol View Scheme
参考文献
Journal of medicinal chemistry, , vol. 15, # 4 p. 436 - 437
反应条件
1: 78 percent / NaOH / a) 20 min, b) reflux, 4 h 2: 88 percent / 3percent H2O2, KOH / H2O 3: 90 percent / Br2, NaOH / H2O / 0.5 h / 75 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 10 p. 2352 - 2357
反应条件
1: 88 percent / 3percent H2O2, KOH / H2O 2: 90 percent / Br2, NaOH / H2O / 0.5 h / 75 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 10 p. 2352 - 2357
反应条件
1: 1.) sodium hydroxide / 1.) RT, 0.5 h, 2.) RT, overnight 2: 62 percent / 10percent aq. KOH / 0.5 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 2 p. 752 - 757
反应条件
sodium hydroxide in tetrahydrofuran
参考文献
Lalezari, Iraj; Lalezari, Parviz
Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2352 - 2357
