1: 1) Mg / 1) THF, reflux, 15 min.; 2) THF, room temperature, overnight 2: 92 percent / H2 / 5percent Pd/C / ethanol / 48 h / 70 °C / 2585.7 Torr 3: 73 percent / 1) Na2CO3, KI / 1) n-butanol, reflux View Scheme

1: 92 percent / H2 / 5percent Pd/C / ethanol / 48 h / 70 °C / 2585.7 Torr 2: 73 percent / 1) Na2CO3, KI / 1) n-butanol, reflux View Scheme

1: 1) Mg / 1) THF, reflux, 15 min.; 2) THF, room temperature, overnight 2: 92 percent / H2 / 5percent Pd/C / ethanol / 48 h / 70 °C / 2585.7 Torr 3: 73 percent / 1) Na2CO3, KI / 1) n-butanol, reflux View Scheme

sodium carbonate; potassium iodide 1) n-butanol, reflux;

1: 98 percent / K2CO3 / acetone / 24 h / Heating 2: 73 percent / 1) Na2CO3, KI / 1) n-butanol, reflux View Scheme