(Z)-3,4,5,4’,-四甲氧基-3’-羟基二苯乙烯合成路线 （共 68 条）
反应条件
1: acetonitrile / 6 h / Reflux 2: potassium hydroxide / ethanol / 5 h / Reflux; Inert atmosphere View Scheme
参考文献
Journal of Chemical Research, , vol. 35, # 4 p. 229 - 230
反应条件
in ethanol T=10 - 14°C; 4 h; sunlight irradiation;
参考文献
Guo, Xiaotao; Zhang, Dan; Yu, Zhifang; Liu, Tianzhen; Li, Dachang; Li, Chunbao
Journal of Chemical Research, 2011 , vol. 35, # 4 p. 229 - 230
反应条件
1.1: methanol; potassium acetate / 0.25 h / Reflux 2.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 12 h / 20 °C 3.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere 3.2: -78 - 20 °C / Inert atmosphere 4.1: quinoline; hydrogen / hexane; toluene / 1 h / 20 °C / 760.05 Torr 4.2: 0.25 h / 20 °C View Scheme
参考文献
Synthesis, , # 22 art. no. Z71911SS, p. 3711 - 3715
反应条件
1.1: methanesulfonic acid; phosphorous pentoxide / 4 h / 40 °C 2.1: methanol; potassium acetate / 0.25 h / Reflux 3.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 12 h / 20 °C 4.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere 4.2: -78 - 20 °C / Inert atmosphere 5.1: quinoline; hydrogen / hexane; toluene / 1 h / 20 °C / 760.05 Torr 5.2: 0.25 h / 20 °C View Scheme
参考文献
Synthesis, , # 22 art. no. Z71911SS, p. 3711 - 3715
反应条件
1.1: 4 h / 135 °C 2.1: methanesulfonic acid; phosphorous pentoxide / 4 h / 40 °C 3.1: methanol; potassium acetate / 0.25 h / Reflux 4.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 12 h / 20 °C 5.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere 5.2: -78 - 20 °C / Inert atmosphere 6.1: quinoline; hydrogen / hexane; toluene / 1 h / 20 °C / 760.05 Torr 6.2: 0.25 h / 20 °C View Scheme
参考文献
Synthesis, , # 22 art. no. Z71911SS, p. 3711 - 3715
反应条件
1.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 12 h / 20 °C 2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere 2.2: -78 - 20 °C / Inert atmosphere 3.1: quinoline; hydrogen / hexane; toluene / 1 h / 20 °C / 760.05 Torr 3.2: 0.25 h / 20 °C View Scheme
参考文献
Synthesis, , # 22 art. no. Z71911SS, p. 3711 - 3715
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere 1.2: -78 - 20 °C / Inert atmosphere 2.1: quinoline; hydrogen / hexane; toluene / 1 h / 20 °C / 760.05 Torr 2.2: 0.25 h / 20 °C View Scheme
参考文献
Synthesis, , # 22 art. no. Z71911SS, p. 3711 - 3715
反应条件
1: sodium hydride / dichloromethane / 14 h / 0 - 20 °C 2: ethanol / |UV-irradiation 3: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / 5 - 10 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 56, p. 166 - 178
反应条件
1: C50H61Br2MoN2O2Si / benzene / 4 h / 22 °C / 100 Torr / |Glovebox 2: tetrakis(triphenylphosphine) palladium(0); caesium carbonate / tetrahydrofuran; water / 66 °C / |Glovebox View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 16 p. 6026 - 6029
反应条件
1: lithium bromide / tetrahydrofuran 2: toluene 3: n-butyllithium / tetrahydrofuran / -20 °C 4: tetrabutyl ammonium fluoride / tetrahydrofuran View Scheme
