1-(3-氯-4-甲基苯基)-2-硫脲合成路线 （共 4 条）
反应条件
ammonia in methanol; acetonitrile T=20°C; 2 h;
参考文献
CELGENE CORPORATION; MULLER, George, W.; RUCHELMAN, Alexander, L.
Patent: WO2010/53732 A1, 2010 ;
Location in patent: Page/Page column 75-76 ;
反应条件
sodium hydroxide T=80 - 85°C; 0.133333 h;
参考文献
Rasmussen, C. R.; Villani, F. J.; Weaner, L. E.; Reynolds, B. E.; Hood, A. R.; et al.
Synthesis, 1988 , # 6 p. 456 - 459
反应条件
1: With benzoyl chloride in acetone 1 h; Heating; 2: With sodium hydroxide in water Heating;
参考文献
Narayana; Vijaya Raj; Ashalatha; Kumari, N. Suchetha; Sarojini
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 10 p. 867 - 872
反应条件
1.1: acetone / 0.25 h / Heating 1.2: acetone / 0.5 h / Heating 2.1: aq. NaOH View Scheme
参考文献
Narayana; Ashalatha; Vijaya Raj; Suchetha Kumari
Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 6 p. 1381 - 1389
