3,5-二溴-2-羟基-4-甲氧基苯甲醛合成路线 （共 19 条）
反应条件
potassium carbonate; sodium iodide in N,N-dimethyl-formamide T=20°C; 13 h; Inert atmosphere;
参考文献
Shearman, James W.; Myers, Rebecca M.; Brenton, James D.; Ley, Steven V.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 1 p. 62 - 65
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Ogamino, Takahisa; Ishikawa, Yuichi; Nishiyama, Shigeru
Heterocycles, 2003 , vol. 61, p. 73 - 78
反应条件
sodium acetate; acetic anhydride Heating;
参考文献
Harburn, J. Jonathan; Rath, Nigam P.; Spilling, Christopher D.
Journal of Organic Chemistry, 2005 , vol. 70, # 16 p. 6398 - 6403
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide
T=0°C; 0.25 h;
参考文献
Boehlow; Harburn; Spilling
Journal of Organic Chemistry, 2001 , vol. 66, # 9 p. 3111 - 3118
反应条件
pyridinium hydrobromide perbromide in pyridine
T=50°C; 2 h;
参考文献
Cordoba, Ruben; Plumet, Joaquin
Tetrahedron Letters, 2002 , vol. 43, # 51 p. 9303 - 9305
反应条件
pyridine; pyridinium hydrobromide perbromide
T=50°C; 2 h;
参考文献
Cordoba, Ruben; Tormo, Nelida Salvador; Medarde, Antonio Fernandez; Plumet, Joaquin
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 15 p. 5300 - 5315
反应条件
1: 93 percent / BCl3 / CH2Cl2 / 16 h / 0 - 20 °C
2: 83 percent / pyridinium-hydrobromide-perbromide / pyridine / 2 h / 45 °C
View Scheme
参考文献
Hinterding, Klaus; Knebel, Axel; Herrlich, Peter; Waldmann, Herbert
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 8 p. 1153 - 1162
反应条件
in dichloromethane
T=0°C; 0.75 h;
参考文献
Cordoba, Ruben; Csaky, Aurelio G.; Plumet, Joaquin; Ortiz, Fernando Lopez; Herrera, Rafael; Jimenez-Vazquez, Hugo A.; Tamariz, Joaquin
Tetrahedron, 2004 , vol. 60, # 17 p. 3825 - 3830
反应条件
bromine; sodium acetate; acetic acid
参考文献
Rao; Srikantia; Iyengar
Journal of the Chemical Society, 1929 , p. 1580
参考文献
Henry; Sharp
Journal of the Chemical Society, 1930 , p. 2279,2287
