1-氨基-4-苯基环己烷羧酸合成路线 （共 4 条）
反应条件
sodium hydroxide in ethylene glycol dimethyl ether T=20°C;
参考文献
Chu, Xin-Jie; Bartkovitz, David; Danho, Waleed; Swistok, Joseph; Cheung, Adrian Wai-Hing; Kurylko, Grazyna; Rowan, Karen; Yeon, Mitch; Franco, Lucia; Qi, Lida; Chen, Li; Yagaloff, Keith
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 22 p. 4910 - 4914
反应条件
1: 95 percent / ethanol; H2O / 90 °C 2: 91 percent / Et3N; DMAP / tetrahydrofuran / 20 °C 3: aq. NaOH / 1,2-dimethoxy-ethane / 20 °C View Scheme
参考文献
Chu, Xin-Jie; Bartkovitz, David; Danho, Waleed; Swistok, Joseph; Cheung, Adrian Wai-Hing; Kurylko, Grazyna; Rowan, Karen; Yeon, Mitch; Franco, Lucia; Qi, Lida; Chen, Li; Yagaloff, Keith
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 22 p. 4910 - 4914
反应条件
1: 91 percent / Et3N; DMAP / tetrahydrofuran / 20 °C 2: aq. NaOH / 1,2-dimethoxy-ethane / 20 °C View Scheme
参考文献
Chu, Xin-Jie; Bartkovitz, David; Danho, Waleed; Swistok, Joseph; Cheung, Adrian Wai-Hing; Kurylko, Grazyna; Rowan, Karen; Yeon, Mitch; Franco, Lucia; Qi, Lida; Chen, Li; Yagaloff, Keith
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 22 p. 4910 - 4914
反应条件
in 1,4-dioxane; water
T=20°C; pH=11;
参考文献
Chu, Xin-Jie; Bartkovitz, David; Danho, Waleed; Swistok, Joseph; Cheung, Adrian Wai-Hing; Kurylko, Grazyna; Rowan, Karen; Yeon, Mitch; Franco, Lucia; Qi, Lida; Chen, Li; Yagaloff, Keith
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 22 p. 4910 - 4914
