反应条件
1: 9-bromo-2-hydroxy-7-methyl-4H-pyrido[1,2-a]pyrimidin-4-one hydrochloride With triethylamine in tetrahydrofuran T=5°C; 0.166667 h; 2: With methanesulfonyl chloride in tetrahydrofuran T=5°C; 3: morpholine in tetrahydrofuran; water T=20 - 65°C;
参考文献
Fjellstrom, Ola; Gustafsson, David; Lindberg, Jan A.; Jackson, Shaun
Patent: US2009/191177 A1, 2009 ;
Location in patent: Page/Page column 7 ;
US 20090191177 A1
