pyridinium p-toluenesulfonate in methanol T=20°C;

1: tert-butyldiphenyl(prop-2-ynyloxy)silane With n-butyllithium in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide; hexanes T=-45°C; 0.166667 h; Inert atmosphere; 2: oxirane in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide; hexanes T=-45 - 20°C; Inert atmosphere;

1: 96 percent / imidazole / CH2Cl2 / 2 h / 0 °C 2: 78 percent / pyridinium p-toluenesulfonate / methanol / 20 °C View Scheme

1: 96 percent / imidazole / CH2Cl2 / 2 h / 0 °C 2: 78 percent / pyridinium p-toluenesulfonate / methanol / 20 °C View Scheme