6-氯-2-三氟甲基-吡啶-3-胺合成路线 （共 2 条）
反应条件
tris(trimethylsilyl)silyl chloride in acetonitrile T=80°C; 24 h; Inert atmosphere;
参考文献
Wiehn, Matthias S.; Vinogradova, Ekaterina V.; Togni, Antonio
Journal of Fluorine Chemistry, 2010 , vol. 131, # 9 p. 951 - 957
反应条件
1: trichlorophosphate; N,N-dimethyl-formamide / 16 h / 90 °C 2: iron; ammonium chloride / methanol / 2 h / |Reflux View Scheme
参考文献
PHENEX PHARMACEUTICALS AG; STEENECK, Christoph; KINZEL, Olaf; GEGE, Christian; KLEYMANN, Gerald; HOFFMANN, Thomas
Patent: WO2013/79223 A1, 2013 ;
